The Pistol Pestilence mod in Warframe is a highly valuable dual-stat mod that grants both Toxin damage and increased status chance for secondary weapons. This makes it an essential mod for players looking to create status-focused builds for their pistols. Acquiring this mod can significantly improve your overall damage output, especially when paired with other elemental mods to create powerful combinations like Corrosive or Viral. However, the process to get Pistol Pestilence isn’t immediately obvious, especially to new players. This guide will walk you through exactly how to get Pistol Pestilence in Warframe and explain the most efficient methods to farm it.
What Is Pistol Pestilence?
Pistol Pestilence is one of the dual-stat elemental mods in Warframe that adds:
- +60% Toxin Damage
- +60% Status Chance
This mod is only applicable to secondary weapons, making it ideal for building status-based sidearms. Pistol Pestilence is part of the same mod family as other dual-stat mods like Frostbite, Scorch, and Jolt. Because of its ability to greatly increase both damage and status efficiency, it’s a must-have for many high-end builds.
Where to Get Pistol Pestilence
Fissure Missions
In the current Warframe loot tables, Pistol Pestilence can drop from certain mission rotations as a reward. However, it is most consistently obtained through:
Void Fissure Missions (Axi and Neo)
Some rotations in Axi or Neo fissures may drop rare mods including dual-stat status mods. This is not the most consistent way to farm it, but if you’re also grinding for Prime parts, it can be an added bonus.
Grineer Spy Missions Rotation C
The most reliable method of acquiring Pistol Pestilence is through completing Spy missions on Grineer tilesets and focusing specifically on the C rotation. You need to complete all three data vaults without triggering alarms. If successful, you get access to Rotation C rewards.
- Target Planet: Kuva Fortress or Uranus
- Mission Type: Spy
- Target Rotation: C (complete all 3 vaults)
Pistol Pestilence is included in the reward pool for Rotation C on some Grineer Spy missions. Focus on repeating these missions efficiently to improve your chances.
Nightwave Cred Offerings
Occasionally, Pistol Pestilence appears in the Nightwave store and can be purchased with Creds. These offerings rotate weekly, so it’s a good idea to check each rotation. If you’re actively completing Nightwave challenges, you may have enough Creds to simply buy the mod when it becomes available.
Baro Ki’Teer (Rare Case)
Though uncommon, Baro Ki’Teer has been known to sell certain elemental status mods in his bi-weekly visits. Keep an eye on his inventory, especially if the mod isn’t dropping elsewhere. This method is RNG-based and not reliable, but it’s still an option.
Best Mission for Farming Pistol Pestilence
Suggested Mission: Pago, Kuva Fortress
Pago is a level 30-35 Spy mission on the Kuva Fortress. It is widely considered the best place to farm Pistol Pestilence for the following reasons:
- High chance to get Rotation C reward if all vaults are unlocked undetected
- Decent enemy level for experienced players
- Good drop table for other dual-stat mods
Make sure to bring a Warframe suited for stealth, such as Ivara, Loki, or Octavia. These frames help you complete spy vaults without triggering alarms, ensuring that you get the best possible reward from the mission.
Tips for Efficient Farming
Use Stealth Warframes
To complete spy missions efficiently and access Rotation C, you must avoid triggering alarms. Warframes like:
- Ivara: Use Prowl to stay invisible and bypass traps
- Loki: Switch Teleport and Invisibility help you move fast without detection
- Octavia: Her Mallet and Metronome can be used creatively to distract enemies
Memorize Vault Layouts
Each spy mission has a few different vault layouts. Over time, you’ll recognize them and know the best path to take. You can also practice in the Simulacrum or look for custom Spy Vault tutorials online for specific planet tilesets.
Equip Loot Radar Mods
Use loot radar or enemy radar mods to avoid unnecessary enemy engagements. This also helps you find alternative paths or lockers for extra resources during your runs.
Farm in a Squad (Optional)
If you prefer to run missions quickly, having a squad where each player handles one vault can make the process much faster. However, stealth play is often easier when done solo to avoid accidental alerts.
Trading for Pistol Pestilence
If you’re not having luck farming the mod, another option is to trade with other players. Pistol Pestilence is a tradeable mod, and many veteran players often have extras they’re willing to sell. You can visit trading hubs like Maroo’s Bazaar or use in-game chat to find sellers.
- Expected Platinum Price: 1025 platinum depending on demand
- Best Time to Trade: Weekends or after Prime unvaultings
Buying the mod may save you time, especially if you’re focused on other farming goals. Make sure to compare prices across sellers to get a fair deal.
Using Pistol Pestilence Effectively
Pairing With Other Elemental Mods
Once you have the Pistol Pestilence mod, you can pair it with other dual-stat mods for lethal combinations. For example:
- Pistol Pestilence + Frostbite: Creates Viral damage (Toxin + Cold)
- Pistol Pestilence + Jolt: Creates Corrosive damage (Toxin + Electric)
These combinations are especially useful for high-level missions, Eidolon hunting, or Steel Path content where status effects are essential.
Best Weapons for Status Builds
Secondary weapons that work well with Pistol Pestilence include:
- Kuva Nukor
- Sporelacer Kitgun
- Akvasto Prime
- Tenet Cycron
Look for weapons with high status chance and decent fire rate to get the most out of the mod. Combining with Galvanized mods will further enhance your performance.
Getting Pistol Pestilence in Warframe requires patience, strategy, and a bit of RNG luck. The most consistent way to farm it is by completing Grineer Spy missions and unlocking all vaults for a chance at the Rotation C reward pool. Alternatively, keep an eye on Nightwave Cred offerings or trade with other players if you’re short on time. Once acquired, this mod can completely change your secondary weapon builds, making them more lethal and effective across all types of content. Invest in the right gear, learn your spy missions, and you’ll be well on your way to owning one of the most powerful status mods in Warframe.