Systemic

Scleroderma and systemic sclerosis are terms often used interchangeably in medical contexts, but understanding the distinctions between them is crucial for accurate diagnosis, treatment, and management. Both conditions involve the abnormal hardening and tightening of the skin and connective tissues, which can lead to significant physical and organ-related complications. While scleroderma primarily refers to the … Read more

Systemic sclerosis polymyositis overlap is a complex autoimmune condition where features of systemic sclerosis (SSc) and polymyositis (PM) coexist in the same patient. This overlap syndrome combines the fibrotic and vascular manifestations of systemic sclerosis with the inflammatory muscle involvement characteristic of polymyositis. The combination of these two disorders can present unique diagnostic and therapeutic … Read more